Since primary brain tumors account for only 1-2% of all cancers, most doctors aren’t very familiar with brain tumors. At UVA, our neuro-oncology doctors only see patients with neuro-oncologic disorders, and they’re up to date on standard and experimental treatments.
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Our treatments for neurological cancers include:
- Intraoperative MRI (IMRIS™)
- Gamma Knife
- Molecular cytogenetics, which helps doctors see which brain tumors will respond best to chemotherapy
- Advanced brain-imaging technology
We also assess and treat other problems related to brain tumors and cancer treatment, including changes in memory, speech, personality or emotions. We are always working on new treatments through clinical trials.
We also offer help with related difficulties, such as re-entering the job force, school issues, disability and health-insurance concerns through a variety of support services for people with brain tumors.
Glioblastoma has a reputation for being the deadliest of brain cancers, a disease that rapidly spreads with no avail until now. UVA’s Benjamin W. Purow, MD, has identified an enzyme that appears to control multiple signaling pathways in glioblastoma cells – an enzyme that can shut down those pathways and potentially help save lives.
Join a Clinical Trial
Tumor Vaccine Trial
Based on promising results from a phase II clinical trial, Celldex has opened a phase III trial of the tumor vaccine rindopepimut (CDX-110) in patients with newly diagnosed glioblastoma. Patients must enroll in the study before beginning radiation and chemotherapy.
Trials for Malignant Tumors
We have several new clinical trials for patients with malignant brain tumors.
UVA, in conjunction with Harvard Medical School, is now offering a new clinical trial for patients with recurrent high-grade glioma (glioblastoma and anaplastic glioma) using a new angiopoietin-neutralizing agent AMG386 with and without bevacizumab (Avastin®).
Trial for Gliomas, Glioblastomas
We are conducting a phase I clinical trial of an anti-angiogenic, anti-endoglin antibody in conjunction with bevacizumab in patients with recurrent anaplastic gliomas and glioblastomas.
- Drs. James Larner, David Schiff (left) and Mark Shaffrey were all named in the latest edition of America’s Top Doctors; all were also listed in the companion America’s Top Doctors for Cancer.
- UVA is ranked as one of the top cancer centers in the country by U.S. News & World Report
- UVA is one of only two National Cancer Institute (NCI)-designated Clinical Cancer Centers in Virginia. To be recognized by the NCI, a center must have a substantial portfolio of cancer research support and a scientific staff recognized for its cancer research skills in a wide array of scientific areas.
A Team Approach to Treating Brain Tumors
At UVA, we believe in offering our patients and their families advanced brain tumor treatments within a coordinated, team-based approach that’s dedicated to maximizing quality of life. Our team — which includes surgeons, medical oncologists, pathologists, nurses, social workers, nutritionists and more — meets regularly to discuss each patient’s care plan and improve patient care.